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Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome

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In keeping with the longevity of their role, M2 macrophages independently stimulated with IL4, signal transducer and activator of transcription 6 (STAT6) and PPAR-coactivator-1 (PGC-1) engage an anti-inflammatory phenotype and rely on fatty acid oxidation (FAO) to generate ATP (42)
