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The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

doi: 10.1002/ctm2.70098 137 RongKWangDPuXZhangCZhangPCaoXet al

The challenge with it though is skin penetration

Benedetti A, Comporti M, Esterbauer H

Beyond disease control, biologics have significantly improved quality of life, reduced hospitalizations, and decreased the need for surgeries, making them a cornerstone of modern IBD treatment [41]

Compared to the other tags we mentioned above, these reagents are less expensive which is a major reason that nickel affinity chromatography is so widely used (Table 3)
