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Higher risk factors were a history of type 2 diabetes, tobacco use and advanced chronic kidney disease ( stage 3)

Preparation for the drugs Morphine hydrochloride (batch number 310216, PPPOMN BPOM, Indonesia) and naloxone hydrochloride (batch number B0120414, PPPOMN BPOM, Indonesia) were provided by the Indonesian Food and Drug Authority (BPOM)

Chang A et al

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doi: 10.1212/01.CON.0000450970.99322.84
The assessment of neuronal activation using cFos as a surrogate marker in response to an acute administration of cagrilintide and sCT in chow-fed mice revealed that both cagrilintide and sCT produced a significantly higher cFos signal compared to vehicle-treated mice, showing similar activation patterns in WT mice AP, NTS and LPBN brain areas