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This can lead to severe deficiency and the development of anemia

Table 1 Main indications and administration routes for B 12 treatment Evidence from animal and human studies shows that B 12 also has neuroprotective and anti-inflammatory properties,15 and intervention studies in humans have reported beneficial effects of better B 12 status or B 12 therapy in multiple sclerosis,16 Parkinsons disease,17 myalgic encephalomyelitis,18 autism,19 and (administering very high doses of methylcobalamin) in amyotrophic lateral sclerosis.20 Subcutaneous administration is sometimes recommended when intramuscular injections are contraindicated, for instance, in people using anticoagulants

The solution should be clear to slightly blue-tinted from the copper in GHK-Cu

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This requires maintaining the water quality within tight parameters during the initial 8 to 12 weeks , which can be difficult to accomplish

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