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Description
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16, dehydroascorbate is converted back to ascorbic acid by the enzyme dehydroascorbate reductase
Both 3-MP and Na 2 S rescued cell viability following cotreatment with DMF and FG4592 (Supplemental Figure 11, B and C)
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Wilson TD, Forde isoMD, Crain AVR et al
Clinical evaluation can later be expanded to other target drug metabolizing enzymes and transporters using larger probe cocktails (five to six object drugs), which may reveal other drug interactions that were either not tested or missed in vitro (Nguyen et al., 2021)
