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Since the CCK-8 assay is based on the dehydrogenase activity detection in viable cells, conditions or chemicals that affect dehydrogenase activity in viable cells may cause discrepancy between the actual viable cell number and the cell number determined using the CCK-8 assay

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3d, we show that treatment with ENDO3 decreased the detection of phosphorylated IRF7 in Cal1 cells in a time-dependent manner, supporting that the compound inhibits CpGTLR9 downstream signaling

however, the sensory behaviors and sensory processing of these mutants appears to be defective and are similar to the traits observed in ASD

The diverse chemical strategies for achieving selective payload release in infectious disease settings are summarized in Table 3, which catalogs linker classes, their activation triggers, and representative applications across ID/NTDs