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American Journal of Clinical Dermatology

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No validated outcome measures

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In addition, in the B12 deficient group, biochemical parameters such as folate (22.4 vs 14.9 nM) and HDL cholesterol (1.4 vs 1.7 mM) levels were significantly lower, whereas TG (3.5 vs 2.9 mM) was higher

Conclusion This systematic review and meta-analysis indicate that sublingual and oral vitamin B12 administration provide efficacy comparable to intramuscular injection in improving serum cobalamin levels and reducing hyperhomocysteinaemia