paracetamol and glutathione depletion Data summary: IL-4 regulates levels in the liver lung Glutathione Depletion in Mitochondrial Diseases

Description

The figure is demonstrating predicted pharmacokinetic features of compounds: passive gastrointestinal absorption (HIA), passive brain access (BBB) and active efflux from the central nervous system or to the gastrointestinal lumen by P-glycoproteins (PGP+: yes, PGP-: no) based on physicochemical descriptors (WLOGP and TPSA, for lipophilicity and apparent polarity)

Functional GO has two aromatic planes and is capable of adsorbing aromatic compounds via simple physisorption (mainly stacking and hydrophobic interactions) 42

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