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In the present study, we administered either NAC or ALC intrathecally for 4 weeks using osmotic minipumps and found marked neuroprotective effect on lesioned spinal motoneurons with almost complete restoration of density of dendritic branches and axonal terminals in the ventral horn

The bile acids, deoxycholic acid and ursodeoxycholic acid, regulate colonic epithelial wound healing

[DOI] [PubMed] [Google Scholar] 28.Silvester KR, Cummings JH

Carnitine also has osmoprotective properties, which can inhibit the activation of transient receptor potential vanilloid type 1 (TRPV1) and protect corneal and conjunctival cells from hyperosmotic stress in dry eye [320]

[55], showed that rats, orally receiving radiolabeled LC, metabolized it to -butyrobetaine (up to 31% of the administered dose, present primary in feces) and TMAO (up to 23% of the administered dose, present primary in urine)

10.1681/ASN.2015111285 3 BainM