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Nevertheless, currently available DNMT inhibitors are not sufficiently selective, leading to off-target adverse effects including global DNA hypomethylation, oncogene activation and increased genomic instability

[PubMed] [Tandfonline] Murphy MM, Fernadez-Ballart, JD

[DOI] [PubMed] [Google Scholar] [112].Xie Y, Zhu S, Zhong M, et al

Disturbances of amino acid metabolism: clinical chemistry and diagnosis

Instead, cells undergoing ferroptosis have only subtle differences in their morphological features, like smaller-than-normal cell volume and increased mitochondrial membrane density
