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Possible B12 injection side effects tend to be mild and short-lived, and may include: Injection site pain, redness, or swelling Mild itching Brief diarrhea (less common) A feeling of warmth after the injection Serious side effects are rare

Overall, if you have enough vitamin B12 in your body, you should have an increased level of cognitive functioning, and energy, and are more likely to be in a good mood

Methylcobalamin: a potential vitamin of pain killer
The results support the phenomenon observed in this report, in which vitamin B12 was injected at the swollen nerve roots