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The atomisation of vegetable glycerine, propylene glycol and flavourings in e-liquids produces carbonyl compounds such as formaldehyde, acetaldehyde and acrolein (Famele et al

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Histone 3 lysine 9 acetylation of BRG1 in the medial prefrontal cortex is associated with heroin selfadministration in rats

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Research models show it drives angiogenesis via VEGFR2 signaling and modulates nitric oxide synthesis, accelerating soft-tissue repair at the injury site

Additionally, metabolic profiling has revealed that suppression of GLS1 induces a compensatory anaplerotic mechanism via pyruvate carboxylase (PC), which allows the release of a glutamine-independent supply of TCA intermediates by catalyzing the transformation of pyruvate to oxaloacetate 153