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Importantly, SNAC transiently fluidizes the gastric epithelial membrane, promoting transcellular absorption of semaglutide while preserving tight junction integrity

doi: 10.1080/09537104.2023.2222184 3 SmithANJoshiSChanzuHAlfarHRShravani PrakhyaKWhiteheartSW

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Therefore, higher doses of oral vitamin B12 can still be used in these patients to ensure normal levels of B12

Human data is still early but promising
