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Several classes of GSTs are highly expressed in human cancers, including colon, kidney, pancreatic, and liver cancers, implying cancer-promoting effects (47)

Ashton RS, Banerjee A, Punyani S, Schaffer DV, Kane RS

Notably, high H 2 S concentrations have also been reported in septic shock patients [315]

The HDAC6-specific inhibitor tubastatin A (TS) prevented a high glucose-induced increase in the oxidative/nitrosative stress markers nitrotyrosine and 4-HNE by upregulating the NAD-dependent deacetylase SIRT1 in human retinal endothelial cells (HRECs) [103]

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Visual Overview Abstract Pathological levels of beta amyloid (A) lead to disruption and elimination of synapses in brain as the result of direct neurotoxicity as well as neuroinflammation