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Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling

Subsequent studies identified mitochondrial dicarboxylate carrier (DIC), and the 2-oxoglutarate carrier (OGC) as the protein transporters responsible for GSH influx into mitochondria [126,127]

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In advanced liver disease, for example, the overall metabolic capacity may be so profoundly reduced that the contribution of a specific CYP polymorphism becomes negligible

For example, some sources suggest starting at ~100 mcg for peptides like DSIP, and then adjust only if needed