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Targeted nanoparticle systems have been engineered as well

However, these therapies are often limited by drug intolerance, notable side effects, high recurrence rates, and elevated costs (Ariyaratnam and Subramanian, 2014

Potential side effects could range from mild to severe, including allergic reactions, injection site complications, and systemic effects

Not everyone's methylation pathways work the same way

In the T-cell dependent pathway, ADAs are generated when a T helper cell (Th) differentiates into a Th1 or Th2 phenotype and, following their cognate interactions with B cells, induces the proliferation of plasma cells (PC) that secrete ADAs