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The stimulant drugs such as cocaine, amphetamines and methylphenidate produce many of their CNS actions via molecular interactions with the dopamine transporter (DAT)

(2015) Randomized, double-blind, placebo-controlled pilot trial of reduced coenzyme Q10 for Parkinsons disease

Preclinical studies have used various neurotoxin-based models to mimic the oxidative stress and dopaminergic neurodegeneration observed in PD

Can J Physiol Pharmacol (2018) 96(9):93342

2019 Nov 26;8(12):588

The deterioration and subsequent cognitive impairments of the midbrain nigral dopaminergic neurons distinguish by this characteristic
