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Metabolism of Diosbulbin B In Vitro and In Vivo in Rats: Formation of Reactive Metabolites and Human Enzymes Involved
3.2 Combination Therapy The heterogeneity of cancer metabolism, even within the same tumor [62], poses many challenges for potential drug therapies

Behav Pharmacol 19: 461484, 2008

These findings were recently confirmed and extended by Wilding et al
Archives of Pharmacal Research

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