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K., & Molin, S
At baseline, FARD-1::RFP fluorescence partially overlaps with peroxisomally targeted GFP (Figure 2figure supplement 2C)

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Several studies have shown that SDH-deficient cells exhibit increased tumorigenesis and that this increase is reversed by the addition of -KG, supporting the idea that succinate accumulation contributes to tumorigenesis through epigenetic modification 100

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