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The evidence base is narrow and concentrated, with limited independent replication
Conversely, a more recent 16-week randomized controlled trial ( n = 58) reported that sulforaphane (approximately 45 mg/day) failed to change the severity of psychotic symptoms compared to placebo using the total Positive and Negative Syndrome Scale (McGuinness and Kim, 2020)

Cinar et al., 2018

H.et al (2011)

While microbes and their products can breach the intestinal epithelium during normal cellular processes including luminal antigen sampling, dead cell extrusion, or programmed cell death, their systemic spread is restricted by specialised immune cells residing within the underlying lamina propria (Smith et al
