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Additionally, the pathology is driven by dysregulated stress granule dynamics and impaired selective autophagic clearance of TDP-43 aggregates, particularly regarding persistent stress granules containing TDP-43 [337]

Through the non-specific process of micropinocytosis, extracellular fluids are internalized, as well as dissolved molecules, viruses, and apoptotic cell fragments

Gu Y, Hu J, Wang C, Qi M, Chen Y, Yu W, et al

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Microbes, metabolites, and the gut-lung axis

4) Cytoprotection & Tissue Integrity (Gastrointestinal Concept) Within Roberts cytoprotection/adaptive cytoprotection framework, BPC-157 has been discussed as a stable peptide with broad mucosal-protective properties in preclinical models (Sikiric 2019, review