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To further explore changes between long-chain hydroxylated and non-hydroxylated SHexCers, we examined heat maps of z -scores in the GPi and GPe brain regions (Supplementary Fig

RhlI and RhlR are primarily responsible for the synthesis and detection of N-butanoyl-L-homoserine lactone (C4-HSL), which also promotes the transcription of RhlI, which in turn promotes the expression of virulence factors [79]

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