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A study by Another important enzyme in arachidonic acid metabolism is 5-lipoxygenase (5-LOX), which leads to the production of leukotrienes (Samuelsson et al., 1987)

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doi: 10.1186/s12967023-047931 19 CaiFLiDXieYWangXMaHXuHet al
Vitamin B12 is essential for energy production, nerve function, and red blood cell formation

Though a state of hyperammonemia in sepsis is not a hallmark, it is a sign of poor prognosis [48]

The infiltration of immune cells such as macrophages, neutrophils, mast cells, B cells, T cells, NKT cells within the adipose tissue, coupled with the overproduction of inflammatory mediators and adipokines (e.g., leptin and lipocalin), adipocyte-derived MCP-1 and hypertrophy of visceral adipocytes, leads to hypoxia, autophagy, and apoptosis (130)
