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[5] Experimental findings suggest possible modulation of metalloproteinase expression, collagen-related gene activity, and antioxidant enzyme systems, supporting extracellular matrix turnover

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In this context, strengthening the intestinal barrier integrity has emerged as an attractive therapeutic approach for rheumatoid arthritis (RA) [5]

Overdosing is rare due to vitamin B12s safety profile, though always follow prescribed dosing to avoid complications