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Frazier R, Mehta R, Cai X, Lee J, Napoli S, Craven T, et al

[DOI] [PubMed] [Google Scholar] 53.Vane J.R., Anggard E.E., Botting R.M

"Biosynthesis of the pigments of life: formation of the macrocycle"
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In oral formulations, the native/parent form is used, while in parenteral formulations, the sulfobutyl derivative is used

50 Lastly, low potency opioids such as codeine (3090 mg) or tramadol (50100 mg) can be effective for intermittent RLS but may have side effects including nausea and constipation
