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In hemodialysis patients, due to reduced renal clearance, carnitine depletion and acylcarnitine accumulation become significant, resulting in an abnormal increase in the ratio of acylcarnitine to free carnitine in plasma, which in turn inhibits cardiac fatty acid metabolism [261]
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Wucherpfennig, KW Self-reactive human CD4 T cell clones form unusual immunological synapses J Exp Med 209 2: 335-52
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