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It has been noted that alkaloids, and polyphenols and tannic acid of RAN that are released in the saliva may contribute to carcinogenicity 4,5,6

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But the researchers discovered that after an overdose, liver cells turn on a gene that shuttles desperately-needed cysteine into the cell but pumps glutamate out, until eventually glutamate levels start to run low, too

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Zhou R-P, Chen Y, Wei X, Yu B, Xiong ZG, Lu C, et al

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