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Usually, damaged melanocytes are eliminated through apoptosis and senescence, but research by Ken et al suggests that MSCs depletion may occur due to ectopic differentiation and impaired renewal

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While its ability to influence multiple pathways of repair is supported by compelling preclinical data, the absence of high-quality human trials, the FDAs strict regulatory stance, and the risk of contamination from unregulated sources raise serious safety and legal concerns (including malpractice concerns and fines)

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We found that while the docetaxel decreased the G0/G1 phase, both chlorophyllin and its coadministration with docetaxel led to a slight increase in the G0/G1 phase compared to the control group after 24 h of incubation

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