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For example, Wnt/-catenin signaling promotes -catenin nuclear translocation, where it interacts with T-cell factor/lymphoid enhancer-binding factor (TCF/LEF) transcription factors to activate the expression of target genes regulating cell proliferation, such as c-Myc and cyclin D1

The Arabidopsis NPR1 protein is a receptor for the plant defense hormone salicylic acid

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Disruptions of the TrxR1 system, although not substantially impacting either the cellular redox balance or GSH pools, disrupts embryonic patterning, Nrf2 regulation, and other signaling-dependent processes [49]