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Clinically, RS1 provides sustained fermentation throughout the colon due to its gradual release from the food matrix

Rotation day (for aliquoted protocols): Move next frozen aliquot to fridge the evening before the current aliquot runs out
Considering that TNF levels increased in spinal microglia, and considering the effects of TNF on TNFR1 and R2 in endothelial cells, the subsequent signaling of TNF receptors may increase COX2 and PGIS expression

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