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Inflammation seems to have a key role in fatigue before, during, and after cancer-treatment

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Our previous study demonstrated that the activity of CPT I, a key mediator in the -oxidation of fatty acids, is decreased in the mitochondria of the livers of mice with cachexia liver, and is increased by L-carnitine (3)

L-carnitine is an endogenous HDAC inhibitor selectively inhibiting cancer cell growth in vivo and in vitro

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