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Side effect amplification Some side effects amplify when multiple peptides affecting similar systems combine

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3 In normoxia, HIF1A protein is targeted for degradation by cytosolic prolyl hydroxylases, while in hypoxia, these prolyl hydroxylases are inhibited, allowing HIF1A to translocate to the nucleus, dimerize with HIF1 protein, and the dimer then binds to hypoxia response elements to modulate transcription of target genes, prompting changes in metabolism and angiogenesis to promote survival

Scientists have been studying about this peptide for decades and have found it to have some profound effects on the aging process at a cellular level