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Finally, Drosophila do not have an adaptive immune system, which complicates both the study of tissue restitution after injury and the underlying crosstalk with intestinal microbes

Walsh CJ, Escudero King C, Gupta M, Plant PJ, Herridge MJ, Mathur S, et al
Nat Rev Dis Primers (2016) 2:16057
The stagger is due to the brains balance and motor control centres being scrambled by the alcohol
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10.1038/s41577-019-0240-6 40