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For examination of cytokines and cellular proliferation, the following antibodies were used: TNF (MAb11, 1:200), IFN (4S.B3, 1:200) and Ki-67 (Ki-67, 1:400)

10.1016/j.colsurfb.2021.111616 191 RahimpourY.HamishehkarH

In addition, In vitro studies using human dopaminergic neurons derived from induced pluripotent stem cells (iPSCs) have provided critical mechanistic insights:(1) nicotine (10 M) activates 7 nAChRs to reduce -synuclein oligomerization and mitochondrial fission in PD patient-derived neurons, effects blocked by the selective antagonist -bungarotoxin

10.1016/j.vetmic.01010 29

Figure 4: Drug-Induced Liver Injury