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Nat Biotechnol 28(9):917924

Gwang Ha Kim, Sung Jo Bang, Alexander R

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Decreased RBC lifespan : This has been documented in mice (due to splenic macrophage erythrophagocytosis [Libregts et al 2011]) and cats with inflammation, although the mechanism was not elucidated in cats (Weiss and Kriehbiel 1983)

Using animal models of MS and examining human post-mortem brain tissue, researchers found that fingolimod reduces neuroinflammation by regulating the pathways involved in B12 communication

3941 Inhibiting RAS or the downstream RAF/MEK/MAPK axis can reverse the erastin or RSL3-induced selective cytotoxicity in engineered RAS-mutant tumor cells, possibly because mutant RAS signaling enhances the cellular basal iron by modulating the expression of iron metabolism-related genes