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Regulation of immune functions by non-neuronal acetylcholine (ACh) via muscarinic and nicotinic ACh receptors

Endothelial cell-specific molecule-1 (ESM1), also known as endocan, is a proteoglycan that is released from cells and circulates in the bloodstream (3)

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Studies show that it has a similar mechanism of action as AOD9604

the control only reached 35 % When they blocked VEGFR2 (with the selective inhibitor SU5416), all of these effects disappeared Why it matters: The last point is what holds the study together

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