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Smolle C, Cambiaso-Daniel J, Forbes AA et al (2017) Recent trends in burn epidemiology worldwide: a systematic review

People most at risk include those who: have type 2 diabetes use insulin or sulfonylurea miss meals have recently increased their dose Symptoms of low blood sugar can include: shaking sweating dizziness hunger headache confusion feeling faint If hypoglycaemia is suspected, it should be treated immediately with fast-acting carbohydrates, such as glucose tablets or a sugary drink

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Since many isoforms of PKC are also activated by increases in intracellular Ca 2+ , both these pathways can also converge on each other to signal through the same secondary effector

No clinical signs of toxicity were observed when a dose of 5 mg/kg was administered for 15 days