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In the Kmt2d +/Geo mouse model, treatment with KD for 2 weeks normalizes the global histone modification state corrects the neurogenesis deficiency in the granule cell layer of the dentate gyrus, and rescues the hippocampal memory defects (88)

Huang X, Song Y, Wei L, Guo J, Xu W, Li M

Serums penetrate better than creams

Conditions were compared with the Dunnetts or Tukey multiple comparisons tests

Statistical analysis Data analysis was performed using GraphPad Prism 8, with results presented as means standard error

Findings delineate that E-cadherin-mediated cellcell contacts kindle the Hippo signaling pathway via the neurofibromatosis 2 (NF2) tumor suppressor protein, thus curbing nuclear translocation and activity of the transcriptional co-regulator YAP in epithelial cells [193]
