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Plant Sci 199200:4147

In male F344/N rats marginal increases in terms of testicular interstitial (Leydig) cell adenoma were found albeit the report considered this as equivocal evidence of carcinogenic activity

G.|Chen, J.|Zhang, Y.|Worden, L.|Freed, W

[DOI] [PubMed] [Google Scholar] 218.Abdel-Hamid N.M., Mahmoud T.K., Abass S.A., El-Shishtawy M.M

Twelve samples preserved in 4% paraformaldehyde undergo ethanol dehydration through graded concentrations (85% for 2 h, 95% for 2 h, followed by 100% for 1 h each) before being cleared in xylene and embedded in paraffin

This can damage the fragile peptide structure
