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these stores will usually last 2-4 years without needing to be replenished

However, unnecessary supplementation offers no added benefit if your B12 levels are already normal

Frequently Asked Questions About Liquid B12 Drops

Cold water added to cold powder dissolves more slowly and may not indicate complete dissolution accurately

Research & Education Tool Vitamin B12 Injection Dosage Calculator Enter the vial amount, diluent volume, and target amount to estimate concentration, draw volume on a 1 mL U-100 syringe, and approximate vial yield

So, we recommend using SL vitamin B12 rather than oral and IM, especially in patients who do not tolerate IM injection and patients who need prolonged vitamin B12 supplementation, such as patients with long-term metformin use and patients with pernicious anemia or with gastro-duodenal resection [51,52,53,54]