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Before now, facial pigmentations like melasma and post-inflammatory hyperpigmentation (PIH) could only be treated with a topical prescription, expensive chemical peels or laser therapy

Results demonstrated that AOD-9604 displayed a very good safety and tolerability profile indistinguishable from placebo. Critically, the peptide produced no clinically significant alterations in IGF-1 levels, no glucose intolerance or insulin resistance, and no anti-AOD9604 antibodies in any participant

rather, divide it up into smaller doses to increase its effectiveness

N Engl J Med 349(5):427434 Felmeden DC et al (2003) Endothelial damage and angiogenesis in hypertensive patients: relationship to cardiovascular risk factors and risk factor management

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The amount of water added determines the final mg/mL concentration used in research dosing calculations