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Prediction of STN-DBS for Parkinsons disease by uric acid-related brain function connectivity: a machine learning study based on resting state function MRI

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Tupper HI, Lawson BL, Kipnis P, Patel AR, Ashiku SK, Roubinian NH, et al

It does not cause gastrointestinal symptoms

doi: 10.1007/s00125-012-2685-z

The resulting full activation of Akt results in inhibition of GSK-3 and therefore loss of repression of Nrf2 by -TrCP
