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Clinically, anticholinergic drugs are often used in combination with L-DOPA or dopamine receptor agonists, primarily for the treatment of PD patients with tremor [132]

However, in schizophrenia, reduced CBF impairs this process, exacerbating neuronal damage and cognitive deficits, including auditory verbal hallucinations (AVHs) (126)

In HSCs, sirtuin 3 (SIRT3) preserves genomic stability and mitochondrial integrity, delaying cellular aging by increasing superoxide dismutase 2 (SOD2) activity and reducing oxidative stress

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