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Retrieved 9 November 2019

However, most therapeutic drugs are unable to enter the brain parenchyma to exert their effects due to the presence of the bloodbrain barrier (BBB), so more effective treatments need to be developed for central nervous system diseases

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doi: 10.3389/fmed.2024.1384454 117 KolkhofPLawatscheckRFilippatosGBakrisGL