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Abstract Background Fatigue of unknown origin is a hallmark symptom in chronic fatigue syndrome (CFS) and is also found in 20% of hypothyroidism patients despite appropriate levothyroxine treatment
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Some studies have shown that between 35 and 50% of patients with FM were not working [7]

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The NLRP3 inflammasome, closely related to CRC, is activated by TMAO-induced endothelial inflammation mediated by mitochondrial reactive oxygen species (ROS) (Chen M

CRediT authorship contribution statement Bing Cheng: Writing original draft
