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These data suggest that the majority of LRRK2-mediated phosphorylation signal minimally resides within residues 252-359 of ArfGAP1 (GAP-F5 fragment), although additional less abundant sites are likely to exist outside of this region as suggested by higher phosphorylation of the GAP-F1 fragment (137-415

The search for modalities to combat this overwhelming virus has been underway since the crisis started, and up to this point, there have been many proposed prevention and treatment strategies to supplement the mRNA vaccine being used worldwide to prevent COVID-19 infection

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