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doi:10.1016/j.livsci.2007.01.027 Clay H, Sillivan S, Konradi C (2011) Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia

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This finding is highly consistent with clinical manifestations of PLS patients, supporting the conclusion that DPP1 inhibition has limited impact on host defense functions at therapeutic doses

The proteins tend to aggregate and precipitate out of solution, making their extraction less efficient [Yang et al ., 2021]

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