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GPx-2 knockout mice are also viable (111), as are the double knockout mice deficient in both GPx-1 and GPx-2 (111)

A recent study also revealed the presence of insulin resistance in rosacea, demonstrating significantly higher fasting blood glucose levels in patients with rosacea than in controls [32]

Rather than acting primarily as direct radical scavengers, organosulfur compounds function as indirect antioxidants by potently inducing phase II detoxification enzymes through the Nrf2 pathway