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PIR and NFIC bind to specific promoter regions of GPX4 and act as a pair of complementary regulators of GPX4 expression

This is standard practice for all IV Revival treatments.

Annu Rev Neurosci 35:445462

Battaglia-Hsu, S

Heme Oxygenase-1 Signaling and Redox Homeostasis in Physiopathological Conditions