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Imaging of glutathione and GABA in the brain as biomarkers of Friedreich Ataxia The FARA Grant Program is proud to award a General Research Grant to David Lynch, MD, PhD, William Gaetz, PhD, & Timothy Roberts, PhD at Childrens Hospital of Philadelphia

Through microarray profiling of messenger RNA (mRNA), long non-coding RNA (lncRNA), and circular RNA (circRNA) expression validated by reverse transcription quantitative polymerase chain reaction (RT-qPCR), their research suggests that immunoregulatory ceRNA (competing endogenous RNA) networks involving lncRNA-circRNA interactions constitute potential therapeutic targets [178]

This review summarizes the current role of HHcy in endothelial dysfunction and explores the cellular mechanisms, including ER stress, that contribute to atherothrombosis

Testosterone upregulation of tissue type plasminogen activator expression in Sertoli cells


doi: 10.1016/j.cell.2022.07.025
